By Elke Hattingen, Ulrich Pilatus
This booklet describes the fundamentals, the demanding situations and the restrictions of cutting-edge mind tumor imaging and examines intimately its effect on prognosis and remedy tracking. It opens with an creation to the clinically proper actual rules of mind imaging. for the reason that MR method performs a very important function in mind imaging, the basic features of MR spectroscopy, MR perfusion and diffusion-weighted MR tools are defined, targeting the explicit calls for of mind tumor imaging. the aptitude and the bounds of recent imaging technique are conscientiously addressed and in comparison to traditional MR imaging. by and large a part of the booklet, crucial imaging standards for the differential prognosis of good and necrotic mind tumors are delineated and illustrated in examples. A last part is dedicated to using MR tools for the tracking of mind tumor remedy. The ebook is meant for radiologists, neurologists, neurosurgeons, oncologists and different scientists within the biomedical box with an curiosity in neuro-oncology.
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Extra info for Brain Tumor Imaging
2002). Apart from the amount and pharmacokinetics of different contrast agents, contrast enhancement is a function of vessel permeability and of the delay time between application of the contrast agent and sequence acquisition (Fig. 25). Diffusion-weighted images (DWI) depict infarction after surgery which may be misinterpreted as recurrent tumor when endothelial barrier disruption brings contrast enhancement in the follow-up (Figs. 20 and 26). The DWI signal and the corresponding apparent diffusion coefficient (ADC) also reflect the microstructure of a tumor (diffusion-weighted methods).
Neuroradiology 54(9):989–995 Gnekow AK, Falkenstein F, von Hornstein S, Zwiener I, Berkefeld S, Bison B, Warmuth-Metz M, Driever PH, Soerensen N, Kortmann RD, Pietsch T, Faldum A (2012) Long-term follow-up of the multicenter, multidisciplinary treatment study HIT-LGG-1996 for lowgrade glioma in children and adolescents of the German Speaking Society of pediatric oncology and hematology. Neuro Oncol 14(10):1265–1284 Huisman TA (2009) Pediatric tumors of the spine. Cancer Imaging 9 Spec No A:45–48 Jallo GI, Freed D, Epstein F (2003) Intramedullary spinal cord tumors in children.
2010), which typically shows an affection of the pachymeninges, whereas the leptomeninges are spared. This pattern can easily be differentiated from the MRI characteristics of leptomeningeal dissemination (Fig. 52) (Medina et al. 2010; Warmuth-Metz 2004). Subdural enhancement must not be confounded with leptomeningeal disease. Patients are always without specific symptoms. In case of extensive subdural enhancement, a leptomeningeal dissemination cannot be excluded with sufficient security, and therefore the spinal MRI has to be repeated after about 1–2 weeks.